The IMPACT Study Design

IMPACT: A landmark study

The first multi-center, randomized, prospective, controlled clinical trial of a widely available, non-invasive cognitive training program designed for adult use

The Issue: Brain Health in Aging
Today's older adults are different from their predecessors. They live longer, have lower disability rates, and are proactive in demanding higher levels of healthcare. And their numbers are swelling: the U.S. population of senior citizens is set to double in the next 25 years, reaching 72 million by 2030.

Brain health is a major issue for these millions of people, even when their brains are aging normally. More than ever before, older adults are looking to their physicians for evidence-based guidance on how to best maintain their brain health. They are wise to do so: clinical research shows that early signs of age-related cognitive decline (defined as normal changes in cognition that accompany aging, e.g., memory lapses) can precede changes in activities of daily living (e.g., ability to manage finances), which in turn often precede changes in living situations (e.g., moving into assisted living).

IMPACT: A Landmark Study in Cognitive Aging
The IMPACT study was designed to demonstrate that Posit Science’s brain-plasticity-based cognitive training (a publicly available program) is statistically superior to non-specfic approaches aimed at staying “cognitively active.” In addition, IMPACT examines the extent to which older adults notice the benefits of training in their everyday lives.

The Posit Science Program and SAAGE™ Protocols
Unique from other “brain training” approaches, the Posit Science program used in the IMPACT study is based upon a specific, data-driven understanding of the root causes of age-related cognitive decline. Incorporating the feedback of world-renowned neuroscientists and physicians, we have developed the SAAGE™ protocols that allow the Posit Science program to directly improve fundamental brain function.

SAAGE-Compliant Program Design