Studies on Cognitive Interventions



Studies on Cognitive Interventions | Studies on Functional Outcomes | Studies of Assessment

The studies in this section address the effectiveness of Posit Science programs for improving memory, speed of processing, and other cognitive abilities.

Healthy Aging
Strong scientific evidence demonstrates Posit Science programs improve cognitive abilities in healthy aging adults.

IMPACT Study
The largest clinical trial to examine if a widely available cognitive training program significantly improves cognitive abilities in adults.
Led by distinguished scientists from Mayo Clinic and the University of Southern California, the IMPACT study proves that people can make statistically significant gains in memory and processing speed if they do the right kind of scientifically designed cognitive exercises. Learn more.
ACTIVE Study
The largest clinical trial to examine the effectiveness of cognitive training in adults.
Funded by the National Institutes of Health, the ACTIVE study proves that healthy older adults can make significant cognitive improvements with appropriate cognitive training and practice.
Other Conditions
Research shows highly promising preliminary results on the effectiveness of Posit Science programs for conditions that feature symptoms of cognitive impairment, and many additional studies are currently in progress.
Mild Cognitive Impairment
Cognitive symptoms: difficulty with memory, including trouble remembering names, misplacing items, forgetting details of conversations, etc.

Researchers at the University of California at San Francisco (UCSF) and the University of California at Davis (UCD) have completed a pilot study investigating the effects of Posit Science training on people with MCI. Preliminary results show strong trend data that indicate significant cognitive improvements. Imaging studies of these patients show they maintain these improvements, while those not using the Posit Science training continue the expected decline. These encouraging results highlight the potential of the Brain Fitness Program for MCI treatment, and confirm that larger trials are merited.

View MCI Study Details

Alzheimer's Disease
Cognitive symptoms: memory loss, difficulty with communication, problems performing familiar tasks, disorientation, changes in personality, etc.

Preliminary results from a study conducted by scientists at Yale University show patients with early to moderate Alzheimer’s disease who use Posit Science training trend toward better performance on cognitive tests and report improvement in symptoms related to depression.

Another study on the effects of Posit Science training on early-stage Alzheimer’s disease (AD) patients is nearing completion at UCSF. We will share results when they become available.

View Alzheimer's Disease Study Details

Chemobrain
Cognitive symptoms: difficulty with memory and concentration, an inability to formulate words and thoughts, problems with multi-tasking, etc.

Preliminary phase one results of a pilot trial studying the effects of Posit Science training on breast cancer survivors suffering from chemobrain are complete. Initial findings are very promising: 94 percent of study participants self-reported a positive change in their overall sense of well-being as well as other significant improvements in their quality of life. Learn more about this study.

View Chemobrain Study Details

Schizophrenia
Cognitive symptoms: difficulty with memory, concentration, task completion, disorganized thoughts, etc.

Researchers at Yale University and the San Francisco Veterans’ Medical Administration Center have independently studied the effects of Posit Science training on people with schizophrenia. Both studies found that Posit Science training significantly improves cognitive function in people with schizophrenia.

View Schizophrenia Study Details

HIV
Cognitive symptoms: difficulties with memory, concentration problems, problems with language, etc.

Posit Science has completed a small case study that found an individual with HIV-associated neurocognitive impairment (HIV-associated NCI) improved at speed of processing and auditory word memory tasks after Posit Science training. These promising initial results show the need for a larger, randomized control trial to evaluate the usefulness of Posit Science programs in treating this condition.

View HIV Study Details

Lyme Disease
Cognitive symptoms: difficulty with memory, trouble formulating words and thoughts, problems with concentration.

Posit Science has completed a small initial case study that demonstrated Posit Science training was effective in improving cognitive function in an individual who suffers from cognitive impairment related to Lyme disease. These results indicate the need for a larger, randomized control trial to further evaluate the benefits of the Posit Science programs for treating cognitive effects of Lyme disease.

View Lyme Disease Study Details

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