Studies on Cognitive Interventions
Studies on Cognitive Interventions Studies on Functional Outcomes Studies of Assessment
The studies in this section address the effectiveness of Posit Science programs for improving memory, speed of processing, and other cognitive abilities.
Researchers at the University of California at San Francisco (UCSF) and the University of California at Davis (UCD) have completed a pilot study investigating the effects of Posit Science training on people with MCI. Preliminary results show strong trend data that indicate significant cognitive improvements. Imaging studies of these patients show they maintain these improvements, while those not using the Posit Science training continue the expected decline. These encouraging results highlight the potential of the Brain Fitness Program for MCI treatment, and confirm that larger trials are merited.
Preliminary results from a study conducted by scientists at Yale University show patients with early to moderate Alzheimer’s disease who use Posit Science training trend toward better performance on cognitive tests and report improvement in symptoms related to depression.
Another study on the effects of Posit Science training on early-stage Alzheimer’s disease (AD) patients is nearing completion at UCSF. We will share results when they become available.
Preliminary phase one results of a pilot trial studying the effects of Posit Science training on breast cancer survivors suffering from chemobrain are complete. Initial findings are very promising: 94 percent of study participants self-reported a positive change in their overall sense of well-being as well as other significant improvements in their quality of life. Learn more about this study.
Researchers at Yale University and the San Francisco Veterans’ Medical Administration Center have independently studied the effects of Posit Science training on people with schizophrenia. Both studies found that Posit Science training significantly improves cognitive function in people with schizophrenia.
Posit Science has completed a small case study that found an individual with HIV-associated neurocognitive impairment (HIV-associated NCI) improved at speed of processing and auditory word memory tasks after Posit Science training. These promising initial results show the need for a larger, randomized control trial to evaluate the usefulness of Posit Science programs in treating this condition.
Posit Science has completed a small initial case study that demonstrated Posit Science training was effective in improving cognitive function in an individual who suffers from cognitive impairment related to Lyme disease. These results indicate the need for a larger, randomized control trial to further evaluate the benefits of the Posit Science programs for treating cognitive effects of Lyme disease.




Posit Science programs and technology have been subjected to more rigorous clinical trials with researchers at more universities than any other cognitive training program in the world. And the results are impressive.