The goal of this in-progress study is to determine whether a brain fitness routine improves quality of life measures for people with chronic heart failure.

The goal of this in-progress study is to determine whether cognitive training improves outcomes for veterans suffering from post-traumatic stress disorder (PTSD.)

The goal of this in-progress pilot study is to determine whether cognitive auditory training ameliorates the symptoms of tinnitus.

In this study, 2802 adults aged 65 years or older were randomized to three cognitive interventions or a no-contact control group. Data on 1804 participants were available at both the 2- and 5-year follow-ups. Of the 4 groups, the group that trained with Posit Science programs had the most clinically significant protection against declines in health-related quality of life (HRQoL)at both 2 and 5 years post-training.

Over 2000 participants age 65 and older participated in this study measuring the effects of cognitive training on health-related quality of life (HRQoL) measures. Those who did Posit Science training were shown to have reduced risk of serious declines in HRQoL, while active controls and participants who trained on other types of brain training exercises showed no significant improvement in risk for HRQoL declines.

Speed of processing training protects self-rated health in older adults: enduring effects observed in the multi-site ACTIVE randomized controlled trial

A recent independent study from the ACTIVE Group looked at 1,804 healthy older adults five years after they had just 10 hours of training. They found that the technology in Posit Science’s InSight brain fitness program contributes to better overall health and may even help people live longer. Researchers found a significant difference in overall health and calculated that this difference should reduce their mortality rate by 0.8 percent.

This study in 97 people (mean age 73.71) showed that Posit Science training may enhance the speed at which older adults can perform instrumental activities of daily living.

This study evaluated the effects of 3 different types cognitive training among 1,534 participants on 5-year improvements in 3 cognitive-specific measures of locus of control. The group who trained on Posit Science programs reflected improvements in internal locus of control between baseline and the 5-year follow-up. The researchers concluded that older adults who complete correctly calibrated cognitive training can improve the cognitive-specific sense of personal control over one's life, even at the 5-year mark.

This study in over 1500 people aged 72-92 showed that the Posit Science program independently predicts the number of bumps while walking. Poor performance on the program is correlated with more bumps.

This study of nearly 2000 people 55 and over showed that performance on Posit Science programs is predictive of future at-fault crashes in older adults. Cognitive performance, in particular, is a salient predictor of subsequent crash involvement in older adults. Those who perform poorly in the training are twice as likely to crash than those who perform well.

In a study of 1800 people aged 65-84, researchers showed that poor performance on the Posit Science program was a significant predictor of crash involvement. Those who performed poorly on the program were more than twice as likely to have been involved in a crash in a four year period.

This study of 174 people 55 and over showed that performance on the Posit Science program can predict crash risk. Poor performers are 1.9 times more likely to crash than those who perform well.

This controlled 3-arm study with 95 participants showed that Posit Science visual brain training improved driving safety. During a post-training driving evaluation, it was observed that Posit-trained drivers traveling at 55 MPH stopped 22 feet sooner than drivers in the two control groups and performed fewer dangerous maneuvers overall. The improvement in driving safety persisted in an 18-month follow-up test. Control participants who trained on a traditional driving simulator only showed no improvement in driving safety.

Impaired verbal memory in schizophrenia is a key factor for functional outcome, does not respond to currently available medications, and shows only modest improvement after conventional behavioral remediation. This study of 55 people with schizophrenia showed that a group trained on Posit Science programs showed significant gains in global cognition, verbal working memory, and verbal learning and memory. They also showed reliable and significant improvement in auditory psychophysical performance.

In this study of 43 participants referred to the Bryn Mawr Rehab Adapted Driving Program, Posit Science program performance predicted pass/fail of driving tests better than other visual and cognitive measures.

Meta-analysis of eight studies using different methodologies confirms the importance of the UFOV assessment as a valid and reliable index of driving performance and safety. Recent prospective studies have confirmed a relationship between UFOV performance and future crashes, further supporting the use of this instrument as a potential screening measure for at-risk older drivers.

In older adults, the peripheral vision field, known as the useful field of view (UFOV), reduces in size. This study showed that UFOV field size can be partially recovered by training on Posit Science programs. Older individuals who use Posit Science training improve UFOV perfmorance to levels closer to those of younger people.

This ongoing study is a collaboration between the University of Toronto and Gilda's Club. Approximately 1 in 3 chemotherapy patients experiences chemotherapy-induced memory loss, also known as "chemobrain" or "chemofog." 30 participants suffering from chemobrain are training with the Brain Fitness Program so that researchers can measure memory thresholds before and after training.

People with schizophrenia frequently have impairments in attention ("task engagement") which have been shown to be related to overall functioning. The goal of this study is to test whether the Brain Fitness Program improves task engagement in individuals with schizophrenia.

With 487 participants, the IMPACT Study is one of the largest controlled randomized clinical trial of any brain fitness program to date. Participants in the active group who used the Brain Fitness Program increased their auditory processing speed by 131% and experienced an improvement in memory equivalent to approximately 10 years. Improvements generalized beyond trained tasks to other measures of memory. Three out of four people who used the Posit Science program self-reported positive changes in their everyday lives.